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Korean Journal of Epidemiology 1987;9(1): 49-56.
B형간염의 가족내 집적성과 전파양상에 관한 연구
오희철, 김일순
Familial aggregation and intrafamilial transmission of hepatitis B
Hee Choul Oh, Il Soon Kim
Abstract
This study was carried out in a rural area, Kangwha County to investigate familial aggregation of hepatitis B infection and to obtain knowledge on relative importance of vertical and horizontal transmission of hepatitis B within family members. Eight hundred and twenty eight persons from 391 households were examined for hepatitis B surface antigen(HBsAg)and antibody( anti — HBs)tested by ELISA method in 1984 and 1985. Results are as follows. 1. Strong familial aggregation of hepatitis B infection was observed. 2. Spouse concordance rate of HBsAg positive and both HBsAg and anti-HBs positive were 43.6% and 53.3% repectively, and these rates did not show statistical difference from those of total study population. 3. Mother with positive HBsAg was important to determine their children's HBV infection. 4. Horizontal transmission of hepatitis B between spouses seemed to take minor part of total hepatitis B infection among adults.


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