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Epidemiol Health > Volume 30(2); 2008 > Article
Epidemiology and Health 2008;30(2): 272-280.
DOI: https://doi.org/10.4178/kje.2008.30.2.272    Published online Dec 31, 2008.
Characteristics of major depressive disorder according to family history of depression : A CRESCEND-K (Clinical Research Center for Depression in Korea) study.
Seunghee Jeong, Hyeon Woo Yim, Youngeun Jung, Sunjin Jo, Taeyoun Jun, Sung Won Jung, Minsoo Lee, Jaemin Kim
1Department of Preventive Medicine, College of Medicine,Catholic University, Korea. y1693@catholic.ac.kr
2Clinical Research Coordinating Center of Catholic MedicalCenter, Korea.
3Department of Psychiatry, College of Medicine, CatholicUniversity, Korea.
4Department of Psychiatry, College of Medicine, KeimyungUniversity, Korea.
5Department of Psychiatry, College of Medicine, KoreaUniversity, Korea.
6Department of Psychiatry, College of Medicine, ChonnamNational University, Korea.
Received: Nov 5, 2008  Accepted after revision: Dec 18, 2008
Abstract
PURPOSE:
People with a family history of mood disorder are more likely to have depression. This study compared the characteristics of non-psychotic major depression disorder according to family history of depression.
METHOD:
Subjects were total of 817 persons recruited for the CRESCEND-K multicenter trial. Characteristics of depression and suicide history of patients with and without a family history of depression were assessed. Family history was determined through self-report.
RESULTS:
Of 817 participants, 12.4% had a positive family history of depression. Those with family history of depression reported an earlier age at onset of MDD, and more psychiatric comorbidity. Severity of depression and anxiety were not different according to family history of depression. There were no difference in attempted suicide history, number of attempted suicide and age at onset of 1st attempted suicide according to such a family history.
CONCLUSION:
Patients with family history of depression reported earlier onset of MDD and more history of psychiatric comorbidity.
Keywords: Major depressive disorder; Family history
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