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Cohort profile Korea Nurses’ Health Study and the health of reproductive-aged women: a cohort profile
Chiyoung Cha1orcid , Heeja Jung2orcid , Sue Kim3orcid , Jung Eun Lee4orcid , Kwang-Pil Ko5orcid , Eunyoung Cho6orcid , Hyun-Young Park7orcid , Joong-Yeon Lim8orcid , Bo Mi Song8orcid , Sihan Song8orcid , Soojin Park8orcid , Aram Cho9orcid
Epidemiol Health 2024;e2024048
DOI: https://doi.org/10.4178/epih.e2024048 [Accepted]
Published online: April 30, 2024
1College of Nursing, Ewha Research Institute of Nursing Science, System Health & Engineering major in graduate school, Ewha Womans University, Seoul, Korea
2College of Nursing, Konyang University, Daejeon, Korea
3College of Nursing, Yonsei University, Seoul, Korea
4Department of Food and Nutrition, College of Human Ecology, Research Institute of Human Ecology, Seoul National University, Seoul, Korea
5Clinical Preventive Medicine Center, Seoul National University Bundang Hospital, Seongnam, Korea
6Department of Dermatology, The Warren Alpert Medical School of Brown University, Providence, RI, United States
7Korea National Institute of Health, Cheongju, Korea
8Division of Population Health Research, Department of Precision Medicine, Korea National Institute of Health, Cheongju, Korea
9College of Nursing, System Health & Engineering major in graduate school, Ewha Womans University, Seoul, Korea
Corresponding author:  Aram Cho,
Email: aram.cho127@ewha.ac.kr
Received: 29 January 2024   • Revised: 15 March 2024   • Accepted: 7 April 2024
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The Korea Nurses’ Health Study (KNHS) is an ongoing, large-scale, prospective cohort study of female nurses, focusing on the effects of occupational, environmental, and lifestyle factors on the health of women. The first KNHS survey was performed in 2013–2014 (n=20,613). As of December 2023, 11 follow-up surveys have been conducted. Participants who were pregnant were asked to participate in the early pregnancy survey (n=2,179) and postpartum survey after giving birth (n=2,790). The main variables included sociodemographic, work-related, lifestyle, physical, mental, and women’s health factors. Blood, urine, and toenail samples were collected from a participant subgroup of the first survey (n=1,983). The subgroups of the second survey completed a food frequency questionnaire in 2019 (n=300) and 2021 (n=871). In 2020, a subgroup of the first survey answered a coronavirus disease 2019 (COVID-19)-related survey (n=975). To examine various health-related factors in young adults, new participants were added to the KNHS cohort in the 11th (n=1,000) and 12th (n=1,002) surveys. The KNHS cohort will help identify health and illness determinants in Korean women. Data can be accessed at https://coda.nih.go.kr/frt/index.do.


Epidemiol Health : Epidemiology and Health