The prevalence of latnet Mycobacterium tuberculosis infection (LTBI) in the first-grade high school students in South Korea was 2.1%, which was the lowest level at congregated settings in 2017. For LTBI cases refusing anti-tuberculosis (TB) medication or having poor compliance, additional support should be considered. Eight systematic reviews concluded that vitamin D (VD) deficiency is a risk factor for TB. While three of four South Korean adolescents were VD deficiency, VD supplementation could be a practical remedy to protect LTBI students of refusing anti-TB medication or having poor compliance.
Summary
Korean summary
잠복결핵검진 검사 양성자이면서 항결핵제 복용을 거부하는 고1학생에 대한 사후 조치가 필요하다. 그동안의 연구결과들에 근거할 때, 잠복결핵이 활동성결핵으로의 전환을 억제하기 위해서 비타민 D 보충제의 투여를 검토해 볼 수 있다.
Citations
Citations to this article as recorded by
Vitamin D and the risk of latent tuberculosis infection: a systematic review and meta-analysis Yan Cao, Xinjing Wang, Ping Liu, Yue Su, Haotian Yu, Jingli Du BMC Pulmonary Medicine.2022;[Epub] CrossRef
Association of vitamin D levels and risk of latent tuberculosis in the hemodialysis population Shang-Yi Lin, Yi-Wen Chiu, Hui-Ru Yang, Tun-Chieh Chen, Min-Han Hsieh, Wen-Hung Wang, Yen-Hsu Chen Journal of Microbiology, Immunology and Infection.2021; 54(4): 680. CrossRef
A scoping review on climate change and tuberculosis Bijay Maharjan, Ram Sharan Gopali, Ying Zhang International Journal of Biometeorology.2021; 65(10): 1579. CrossRef
Tuberculosis risk is associated with genetic polymorphisms in the LRP2, CUBN, and VDR genes Sung-Soo Kim, Sang In Lee, Hyun-Seok Jin, Sangjung Park Genes & Genomics.2020; 42(10): 1189. CrossRef
The Korea Centers for Diseases Control and Prevention (KCDC) has announced a control program against latent <i>Mycobacterium tuberculosis</i> infection (LTBI), for a “TB-safe country” this year with the goal of a “TB-free Korea” by 2025. The program includes high school students as one target group; however, some school health teachers and parents have expressed their opposition to this. The 2015 World Health Organization guidelines do not recommend inclusion of asymptomatic high school students in LTBI control programs. Based on this guideline, the KCDC should consider excluding this population from the program.
Summary
Korean summary
질병관리본부는 결핵안심국가를 만들기 위하여 고등학교 1학년생을 포함한 잠복결핵감염 검사사업을 2017년 추진하기로 공고하였다. 그러나 2015년에 발표된 WHO 지침에 따르면 해당 대상자들은 검사대상자로 제시되어 있지않다. 근거중심의 보건정책 추진을 위해서 사업 대상 선정을 재검토할 필요가 있다.
Citations
Citations to this article as recorded by
The cascade of care for latent tuberculosis infection in congregate settings: A national cohort analysis, Korea, 2017–2018 Jinsoo Min, Hyung Woo Kim, Helen R. Stagg, Molebogeng X. Rangaka, Marc Lipman, Ibrahim Abubakar, Yunhee Lee, Jun-Pyo Myong, Hyunsuk Jeong, Sanghyuk Bae, Ah Young Shin, Ji Young Kang, Sung-Soon Lee, Jae Seuk Park, Hyeon Woo Yim, Ju Sang Kim Frontiers in Medicine.2022;[Epub] CrossRef
Latent tuberculosis infection: recent progress and challenges in South Korea Doosoo Jeon The Korean Journal of Internal Medicine.2020; 35(2): 269. CrossRef
Vitamin D supplementation as a control program against latent tuberculosis infection in Korean high school students Eun Hee Kim, Jong-Myon Bae Epidemiology and Health.2018; 40: e2018035. CrossRef
Suggestions for the promotion of evidence-based public health in South Korea Jong-Myon Bae Epidemiology and Health.2017; 39: e2017030. CrossRef
결핵정책에 대하여 찬병 박 Public Health Affairs.2017; 1(1): 13. CrossRef